The prostate specific antigen test is a blood test to measure the level of prostate specific antigen, a protein marker for prostate cancer. The digital rectal examination is a test done by the doctor to examine the size and contour of the prostate. There is still controversy about the optimal time to begin prostate screening. People with other serious illnesses may not benefit from prostate screening, depending on life expectancy for that condition.

These are both done to screen for prostate cancer. In the United States, over 28,000 men are expected to die of prostate cancer in 2008. About 186,000 new cases are expected, the most of any form of cancer including lung cancer.

Like most blood tests, the prostate specific antigen is measured in a sample of blood taken from a vein in your hand or arm. The digital rectal exam is done by your doctor and involves insertion of a gloved finger into the rectum to feel the prostate gland. Since this test is also done for colorectal screening, the rectum can also be examined for abnormal growths and a sample of stool can be taken to look for blood.

You will likely be instructed to avoid ejaculation within 48 hours of testing.

• Age >/= 65
• Family history, especially father or brother with prostate cancer
• African American
• Possibly high fat diet
• Elevated testosterone
• Farmers
• Cadmium exposure
• Tire plant workers
• Painters